This seems like a wonderful time to get back into Games4Mac, and why not start with the Diablo 3 Beta.  Free for this weekend from Blizzard, the guys that bring you Starcraft and World of Warcraft, Diablo 3 is the third title in the Diablo franchise.  You need a Mac running 10.6.8 or higher and a free Battle.net account:

Download the game here: https://us.battle.net/account/download/index.xml

Sign up for Battle.net here: http://www.battle.net